Selected publications.

Mun SH, Bae S, Zeng S, Oh B, Chai C., Kim M, Kim H, Kalliolias G, Dahia C, Oh. Y, Kim T.W.,  Ji J.D., and Park-Min, K.H.  Augmenting MNK1/2 Activation by c-FMS Proteolysis Promotes Osteoclastogenesis and Arthritic Bone Erosion. Bone research accepted

Kaneko K., Chen H., Kaufman M., Sverdlov I., Stein EM., and Park-Min K-H.  Glucocorticoid-induced Osteonecrosis in Systemic Lupus Erythematosus Patients Clinical and Translational Medicine accepted

Bae S, Park PS, Lee YJ, Mun SH, Giannopoulou E, Violante SN, Cross J, and Park-Min, K.H. MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages. Cell Reports, 2021 35(11) 109264

A Krez, J Lane, A Helibronner, K.H. Park-Min, K Kaneko, T Pannelini, D Mintz, D. Hansen,  DJ McMahon, KA Kirou, G Roboz, P Desai, RS Bockman, and Emily Stein. Risk factors for multi-joint disease in patients with glucocorticoid-induced osteonecrosis. Osteoporosis Internationl 2021 Online ahead of Print

Mun SH, Jastrzebski S, Kalinowski J., Zeng S., Bae SY, Eugenia G., Khan N., Drissi H., Shin BJ., Lee SK., Lorenzo J.*, and Park-Min, K.H*. Sexual dimorphism in early osteoclasts demonstrates enhanced inflammatory pathway activation in female cells. Journal of Bone and Mineral Research, 2021 36(6) 1104  *co-corresponding author

Fuji T, Murata K, Mun SH, Bae SY, Lee YJ, Pannellini T, Kang KH, Oliver D, Park-Min, K.H.*, and Ivashkiv L.* MEF2C Regulates Osteoclastogenesis and Pathologic Bone Resorption via c-FOS.  Bone research, 2021 11; 9(1):4 *co-corresponding author

Vertesich V, Sosa B, Niu YZ, Ji G, Turajane K, Mun SH, Xu R, Windhager R, Park-Min, K.H., Greenblatt MB, Bostrom MP, Yang X. Alendronate Enhances Osseointegration in a Murine Implant Model. Journal of Orthopaedic Research, 2021 39(4):719 PMID:32915488

Kim H, Oh B, and Park-Min, K.H. Regulation of osteoclast differentiation and activity by lipid metabolism. Cells 2021 7;10(1):89

Mun SH, Park PS, and Park-Min KH. The M-CSF receptor in osteoclasts and beyond. Experimental and Molecular Medicine 2020 52(8)1239.

Park PS, Zeng S, Bae S, and Park-Min, K.H. NRF2 is an upstream regulator of MYC-mediated osteoclastogenesis and pathological bone erosion Cells, 2020 21(9)9: E2133

Bae SY, Zeng S., and Park-Min KH. Nuclear receptors in osteoclasts. Curr Opin Pharmacol. 2020 19(53);8-17. doi: 10.1016/j.coph.2020.03.002.

Kusnadi A, Park SH, Yuan R, Pannellini T, Giannopoulou E, Oliver D, Lu T, Park-Min KH.*, and Ivashkiv LB*. TNF promotes SREBP activity and binding to inflammatory target genes to regulate macrophage polarization and tissue repair. Immunity. 2019. doi: 10.1016/j.immuni.2019.06.005. *co-corresponding author

Donlin LT, Park SH, Giannopoulou E, Ivovic A, Park-Min KH, Siegel RM, Ivashkiv LB Insights into rheumatic diseases from next-generation sequencing. Nat Rev Rheumatol. 2019. doi: 10.1038/s41584-019-0217-7.

Park-Min KH. Metabolic reprogramming in osteoclasts. Semin Immunopathol. 2019. 41(5): 565-572. doi: 10.1007/s00281-019-00757-0.

Park-Min KH. Mechanisms involved in normal and pathological osteoclastogenesis. Celllular and Molecular Life Sciences 2018. 75(14):2519-2528. doi: 10.1007/s00018-018-2817-9.

Cao C, Ren Y, Barnett AS, Mirando AJ, Rouse D, Mun SH, Park-Min KH, McNulty AL, Guilak F, Karner CM, Hilton MJ, Pitt GS. Increased Ca2+ signaling through CaV1.2 promotes bone formation and prevent estrogen-deficiency induced bone loss. JCI Insight. 2017. 16;2(22). doi: 10.1172/jci.insight.95512.

Bae S., Lee MJ., Mun SH., Giannopoulou., Yong-Gonzalez V., Cross JR., Murata K., Giguère V., van der Meulen M., and Park-Min KH. MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα. J. Clin. Invest. 2017. 127(7):2555-2568. doi: 10.1172/JCI89935. PMID: 28530645.

Murata K., Fang C., Terao C., Giannopoulou EG., Lee YJ., Lee MJ., Mun SH., BaeS., Yuan R., Qiao Y., Furu M., Ito H., Ohmura., Matsuda S., Mimori T., Matsuda F., Park-Min KH.*, and Ivashkiv LB*. Integrated regulation of macrophage signalling and cellular metabolism by hypoxia-sensitive COMMD1 suppresses osteoclastogenesis and pathologic bone resoprtion. Immunity. 2017. 47(1):66-79. Doi: 10.1016/j.immuni.2017.06.018. *co-corresponding author

Lee MJ, Lim E, Mun S.-H., Bae S, Murata K, Ivashkiv L, and Park-Min KH. Intravenous Immunoglobulin (IVIG) Attenuates TNF-induced Pathologic Bone Resorption and Suppresses Osteoclastogenesis by Inducing A20 Expression. J Cell Physiol. 2016. 231(2):449-58. PMID:26189496 doi: 10.1002/jcp.25091.

Zheng HF*, Forgetta V*, Hsu YH*, Estrada K*, Rosello-Diez A*, Leo PJ*, Dahia CL*, Park-Min KH*, Tobias JH*, Kooperberg C*, Kleinman A*,…, and Richards JB. Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Nature. 2015. 526:112 PMID: 26367794. doi: 10.1038/nature14878. *co-first author

Park-Min KH, Elisha Lim, Min Joon Lee, Sung-ho Park, Eugenia Giannopoulou, Anna Yarilina, Marjolein van der Meulen, Baohong Zhao, Nicholas Smithers, Jason Witherington, Kevin Lee, Paul-Peter Tak, Rab Prinjha and Lionel B. Ivashkiv. Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation Nature Communication. 2014 5:5418. PMID:25391636. doi: 10.1038/ncomms6418.

cdc-WCEOtVmk2VY-unsplash.jpg

For more publications, please see the PubMed listing.